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Tri-Biotic
Tri-Biotic
Tri-Biotic
Tri-Biotic
Tri-Biotic

Tri-Biotic

The performance probiotic

A daily sports probiotic combining pre and probiotics to support gut health, endurance, immune resilience and training consistency.

  • 1 capsule for stronger immunity, better digestion & steadier training
  • 80 billion CFU to support gut health and training energy
  • Designed to reduce stomach issues during endurance training
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  • Cologne List Approved
  • 3rd Party Lab Tested
  • Nutritionist Formulated
When to Use

Take 1 capsule daily with water, preferably with food.
For best results, use consistently, especially during hard training blocks, periods of travel or the weeks surrounding competition.

Benefits

Support your gut through hard training
Endurance training, high volume and travel all stress the gut. Bloating is a common issue that can affect training quality. In addition hard training can cause GI disruption and discomfort during or after sessions. Tri-Biotic supports digestive function so your gut works with your training, not against it.

Maintain immune resilience when it matters most
Heavy training blocks suppress immunity. The Lab4 strains have demonstrated a consistent reduction in upper respiratory tract infection frequency across multiple clinical trials. Tri-Biotic keeps your immune system supported so illness doesn't interrupt the work you've put in.

Improve nutrient absorption and energy availability
A healthier gut absorbs more of what you eat and drink. Better nutrient utilisation means more available energy, more effective fuelling and better recovery, without changing anything else in your routine.

Reduce gut disruption during sessions and races
Unexpected gut issues during training or competition are one of the most common and least talked about performance limiters. Tri-Biotic supports gut comfort and predictability so you can focus on the effort, not manage discomfort mid-session.

Build a more consistent training week
Fewer sick days. Fewer gut-related missed sessions. Less time adapting around digestive discomfort. Tri-Biotic works in the background to make your training more reliable week to week.

Key Ingredients

TWK10 (Lactiplantibacillus plantarum)

A clinically studied probiotic strain that supports endurance performance, digestion and immunity.

  • Shown to improve endurance capacity and support lean mass in clinical trials
  • Reduces fatigue markers and supports lactate clearance during intense training
  • Influences the gut–muscle axis to improve nutrient utilisation and training adaptation
  • Backed by over 30 human studies

Lab4

A microencapsulated probiotic with strong clinical evidence for exercise performance, immune support, gut health and recovery.

  • Supports immune resilience and reduces the frequency of upper respiratory tract infections
  • Reduces exercise-induced inflammation and supports recovery between sessions
  • Contributes to gut barrier integrity and digestive comfort under training stress
  • Backed by 35+ human studies

Aquamin


A marine-derived mineral complex that enhances the activity of probiotics.

  • Improves gut microbiota diversity
  • Increases short-chain fatty acid (SCFA) production, a key marker of gut health
  • Helps maintain the digestive barrier and reduce chronic gut inflammation
  • Works alongside Lab4 and TWK10 to improve formulation stability and efficacy


Nutrition breakdown / Inside Every Serving (1 Capsule / 30 Servings Per Container)

Lab4 - 50 billion CFU

  • Lactobacillus acidophilus CUL60
  • Lactobacillus acidophilus CUL21
  • Bifidobacterium animalis subsp. lactis CUL34
  • Bifidobacterium bifidum CUL20
  • Lactobacillus plantarum CUL66

TWK10® (Lactiplantibacillus plantarum) - 30 billion CFU

Aquamin® TG (Lithothamnion sp.) - 100mg

Total CFU per serving: 80 billion

Gluten Free · No Soy · Vegan

Supporting Research

Effect of Lactobacillus Plantarum TWK10 on Improving Endurance Performance in Humans – 6-week double-blind trial found TWK10 improved endurance performance and glucose content during maximal treadmill running, suggesting better energy. [pubmed.ncbi.nlm.nih]

Effect of Lactobacillus plantarum TWK10 on Exercise Physiological Adaptation, Performance, and Body Composition in Healthy Humans – 6-week placebo-controlled trial found TWK10 improved exercise performance in a dose-dependent manner and improved fatigue-related features linked to better physiological adaptation. [pubmed.ncbi.nlm.nih]

Lactobacillus plantarum TWK10 Improves Muscle Mass and Functional Performance in Frail Older Adults – Human study found TWK10 improved muscle mass, grip strength, lower-limb strength, gait speed, and balance, with larger effects over longer supplementation. [pubmed.ncbi.nlm.nih]

Effects of Probiotics Supplementation on Gastrointestinal Permeability, Inflammation and Exercise Performance in the Heat – 4-week study found probiotic supplementation increased run time to fatigue in the heat and may help support gut integrity under stress. [pubmed.ncbi.nlm.nih]

Effects of heat-killed Lactiplantibacillus plantarum TWK10 on exercise performance, fatigue, and muscle growth in healthy male adults – 6-week clinical trial found heat-killed TWK10 significantly increased exercise endurance time and improved fatigue and muscle-related outcomes. [pubmed.ncbi.nlm.nih]

A comprehensive approach, based on the use of Caenorhabditis elegans, mouse, and human models, elucidates the impact of Lactiplantibacillus plantarum TWK10 on exercise performance and longevity – Human data showed TWK10 improved grip strength and exhaustion time while lowering lactate and ammonia versus control. [pubmed.ncbi.nlm.nih]

Four weeks of probiotic supplementation reduces GI symptoms during a marathon race – Marathon runners taking probiotics had fewer and less severe GI symptoms, and better maintenance of running speed in the final third of the race. [pubmed.ncbi.nlm.nih]

A double-blind, randomised, placebo-controlled study assessing the impact of probiotic supplementation on the symptoms of irritable bowel syndrome in females – 8-week trial found the Lab4 probiotic significantly reduced IBS symptom severity, anxiety, and depression versus placebo.[pubmed.ncbi.nlm.nih]

Probiotic supplementation increases carbohydrate metabolism in trained male cyclists – 4-week crossover trial found probiotics increased carbohydrate oxidation and reduced fat oxidation during cycling, suggesting improved fuel utilisation.[pubmed.ncbi.nlm.nih]

Effects of Probiotics Supplementation on Gastrointestinal Permeability, Inflammation and Exercise Performance in the Heat – 4-week study found probiotic supplementation increased run time to fatigue in the heat and may help support gut integrity under stress.[pubmed.ncbi.nlm.nih]

A Multi-Mineral Intervention Improves Intestinal Permeability in Ulcerative Colitis Patients – 90-day Aquamin trial reduced intestinal permeability and was well tolerated, supporting gut barrier function.[pubmed.ncbi.nlm.nih]

A multi-mineral intervention to improve disease-related and mechanistic biomarkers in ulcerative colitis patients – 180-day trial found Aquamin improved inflammatory and barrier biomarkers and increased hip strength index.[journals.plos]

A Calcium-Rich Multimineral Intervention to Modulate Colonic Microbial Communities and Metabolomic Profiles in Humans – 90-day human study found Aquamin changed colonic microbial and metabolomic profiles in a way consistent with improved gut health. [pubmed.ncbi.nlm.nih]

Optimised Gut Barrier Proteomic Expression And Function With A Multi-Mineral Intervention – Human colon data showed Aquamin upregulated gut barrier proteins and proteins with anti-inflammatory potential. [academic.oup]

An Exploratory Investigation of Endotoxin Levels in Novice Long Distance Triathletes, and the Effects of a Multi-Strain Probiotic/Prebiotic, Antioxidant Intervention – Exploratory triathlete study examined endotoxin and GI-related outcomes, providing additional supportive context for gut-focused performance supplementation. [https://doi.org/10.3390/nu8110733]

Safety Assessment of Lactiplantibacillus plantarum TWK10 Based on Complete Genome Sequence and In Vitro and In Vivo Evaluations – Safety assessment supported the strain’s safe use.

Shipping, Subscriptions & Returns
Shipping


UNITED KINGDOM

We aim to dispatch your orders the same working day if the order is placed before 1pm. Any orders after this will be dispatched the following working day.

Our shipping options are : 

  • Standard 2-4 working days £3.95
  • Express 1 - 2 working days £5.95.

All orders over £50 qualify for FREE standard shipping, note a paid upgrade to express is still possible.

INTERNATIONAL
Similarly to domestic shipping We aim to dispatch your orders the same working day if the order is placed before 1pm GMT. Any orders after this will be dispatched the following working day.

Shipping rates vary depending on country and region but free shipping is available depending on order size for the USA, Australia, Europe and the UAE and international shipping starts at £7.

Subscriptions

You can edit your subscription here: LINK
Please note it is possible to delay your subscription delivery date as well as change an item as opposed to cancelling.

Returns

You have 14 days from the date of receiving your item to initiate a return with us. Exchanges are eligible for free return postage - you can exchange for another size or product permitting the item you ordered has not been used or in the case of supplements has not been opened.  

You can find the return portal here: LINK

*refunds are charged a £3.99 handling fee - this will be deducted from your refund
Bottles are non returnable.

Peak Endurance

STACKS WELL WITH

Supports performance output alongside gut and immune foundations.

£37.00

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Written by Liam Holmes

Probiotics for Endurance Training

The first performance probiotic built to support what the everyday athlete actually needs. Gut resilience, immune strength and training consistency.
Understand what Lab4 and TWK10 can actually do for you.

Written by Liam Holmes

Probiotics for Endurance Training

The first performance probiotic built to support what the everyday athlete actually needs. Gut resilience, immune strength and training consistency.
Understand what Lab4 and TWK10 can actually do for you.

What to Expect Over Time

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Premium quality standards

The MARCHON Standard is an internal framework supported by independent third-party testing and registered bodies, ensuring the efficacy, quality, and integrity of every product we create.

Premium quality standards

The MARCHON Standard is an internal framework supported by independent third-party testing and registered bodies, ensuring the efficacy, quality, and integrity of every product we create.

FAQs

What is Tri-Biotic?

Tri-Biotic is a performance probiotic combining Lab4®, TWK10® and Aquamin® TG, three clinically studied ingredients formulated to support gut health, immune resilience and training consistency in athletes training hard year-round.

Who should take Tri-Biotic?

It's designed for endurance athletes, hybrid athletes, HYROX competitors and anyone training at high frequency or volume. It's particularly valuable during heavy training blocks, periods of travel, and in the weeks surrounding competition. If you regularly experience gut issues during training or pick up illness during hard phases, this was designed for you.

How is this different from a standard probiotic?

Most probiotics are formulated for general gut health and use generic strains with limited sports-specific evidence. Tri-Biotic combines two of the most clinically researched performance strains available, Lab4® (35+ human studies) and TWK10® (30+ human studies) alongside Aquamin® TG to enhance delivery and efficacy. This is a performance probiotic, not a generic gut supplement.

How many CFU does it contain?

80 billion CFU per capsule. 50 billion from the Lab4® strains and 30 billion from TWK10®. This is one of the highest-dose sports probiotics available in the UK.

When should I take it?

Once daily with water, preferably with food. Timing matters less than consistency, the evidence base sits at 4 to 12 weeks of daily use, which is where the meaningful benefits build.

How long before I notice a difference?

Some users notice improved digestive comfort and less bloating around training within the first one to two weeks. Immune resilience and training consistency typically improve over months one to three with consistent daily use.

Can I take it alongside other MARCHON products?

Yes. Tri-Biotic stacks well with Advanced Multivitamin, Collagen+, Peak Endurance and Performance Hydration as part of a complete daily performance routine.

Is it suitable for long-term use?

Yes. Tri-Biotic is designed for consistent, ongoing daily use. There's no cycling required. However a practical way to utilise it is in 3 -6 month blocks based around hard training and competition. You can then come off for 1-3 months until your next hard training block starts.

Is it vegan?

Yes. Tri-Biotic is gluten free, contains no soy ingredients and is fully vegan.